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  690. بررسی اثر ملاتونین و گاباپنتین در کاهش اضطراب و
    درد ناشی از پونکسیون لومبار در کودکان
    مطالبی که در مقاله بالا ذکر شد، فقط و فقط جنبه
    آگاهی بخشی و افزایش اطلاعات شما
    دوستان عزیز را دارد و به هیچ وجه جایگزین توصیه پزشک متخصص
    نیست. لازم است برای مصرف کردن دارو و دانستن عوارض جانبی آن باتوجه به سوابق پزشکی خود با دکتر متخصص مشورت کنید.
    اگر درد کمر از دردهای نوروپاتی و
    عصبی باشد، قرص گاباپنتین یا کپسول گاباپنتین می‌تواند موثر باشد.
    اما برای دردهایی که مشکل آنها عصبی نیست،
    نمی‌توان از این دارو کمکی گرفت.
    متاسفانه یکی از مشکلاتی که گاباپنتین برای مصرف کنندگان خود ایجاد می‌کند،
    بالا بردن قند خون است. هنگامی که قند خون
    بیمار به طور معمول بالا باشد، مثلا بیمار دیابتی باشد، این دارو می‌تواند در تنظیم قند خون برای او مشکلاتی ایجاد
    کند. برای اطلاع از موارد مصرف، نحوه مصرف، عوارض و تداخلات
    دارویی این دارو بهتر است از سرویس
    مشاوره دارویی دکترتو استفاده کنید.
    قبل از تجویز این دارو، پزشک را از بیماریهای افسردگی،گوارشی، دیابت
    ومشکلات کلیوی خود مطلع سازید.
    این دارو در اشکال قرص و یا کپسول در سه
    دوز؛ ۱۰۰ ، ۳۰۰ ، ۴۰۰ گرمی تولید و عرضه می شود.
    و با نام تجاری نوروپنتین،
    گابارون، نورنتین و … شناخته می شود.

    علائم ترک ، که اغلب شبیه علائم ترک بنزودیازپین است ، در وابستگی جسمی برخی
    از کاربران نقش دارد. حدود 1 درصد از جمعیت عمومی و
    22 درصد از کسانی که در مراکز ترک
    اعتیاد شرکت می کنند سابقه سو استفاده از گاباپنتین را دارند.

    سو استفاده از این دارو به دلایلی از جمله خوددرمانی
    ، خودآزاری و استفاده تفریحی ثبت شده است.
    ترکیبی از گاباپنتین با مورفین ، اکسی کدون
    ، یا نورتریپتیلین بهتر از مصرف یک دارو به کار می رود.

    ترکیب گاباپنتین و ونلافاکسین ممکن
    است بهتر از گاباپنتین باشد.
    در صورتی ‌که هر یک از علائم گفته شده را
    تجربه می‌کنید فوراً با پزشک تماس بگیرید.

    وزن مولکولی کم این دارو و عدم توانایی اتصال آن با
    پروتئین‏های پلاسما، احتمال عبور این دارو را از سد خونی- جفتی قوت می­بخشد (13 و 14).
    تحقیقات نشان می‏دهد مصرف این دارو در زمان بارداری می­تواند باعث ایجاد هیدرونفروز و هیدرواورتر در جنین موش گردد .
    علی‏رغم بروز ناهنجاری­های فوق، درهنگام مقایسه با گروه شاهد، مصرف
    داروی گاباپنتین در زمان اندام­سازی فقط
    از نظر افزایش ناهنجاری­های هیدرواورتر و هیدرونفروز معنی­دار بود.

    در رابطه با اثرات تراتوژنیک مصرف این دارو در زمان بارداری اطلاعات
    زیادی در دست نیست لذا ضروری به‏نظر می‏رسد تا مطالعات بیشتری بر روی اثرات ناهنجاری این ماده صورت
    پذیرد.
    گاباپنتین برای مدیریت نورالژی پس از هرپس
    یا علائم پاهای بیقرار در کودکان
    بررسی نشده است. داروی گاباپنتین
    ممکن است وارد شیر مادر شده و بر روی نوزاد تاثیراتت
    بدی داشته باشد. اگر در حال شیردهی به نوزاد خود هستید،
    در مورد مصرف دارو با پزشک مشورت کنید.

    برای پیشگیری از بروز هر گونه تداخل دارویی مصرف داروهای خود را به دقت
    مدیریت کنید. حتما مصرف هر
    گونه دارو، ویتامین یا گیاهان دارویی خود را
    به پزشک اطلاع دهید.

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  702. BENGALURU, Oct 7 (Reuters) – India’s southern state of Karnataka has asked cab aggregators Uber, SoftBank-backed Ola and Rapido to stop three-wheeler services in Bengaluru, a top government official said, accusing them of overcharging and harassing customers.

    “They are not authorised to ply autos… They are charging exorbitantly and it’s a serious complaint,” Hemantha Kumara, additional commissioner for transport, Bengaluru, told Reuters.

    “We can’t tolerate harassment meted out to customers and justify the exorbitant rates,” he said, adding the transport department issued a notice to the companies to stop the service in India’s IT hub on Thursday.

    Ola and Uber India declined to comment.

    Uber in recent weeks has been running television ads on its autorickshaw service in India.

    The country is a growth market for ride-hailing companies as people seek to avoid driving in congested roads and autorickshaws, or tuk-tuks, are one of the most economical modes of short travel.

    Rapido said its operations in Bengaluru are not illegal and it will respond to the notice.

    “All our fares are determined in accordance with the fares decided upon by the state government, and Rapido is not charging any extra money over those fares,” the company said in a statement.

    Last month, India’s competition regulator had said that surge-pricing adopted by cab aggregators in the country appeared to be a ‘Black Box’ for customers and urged for transparency.

    (Reporting by Nallur Sethuraman and Rama Venkat in Bengaluru; Editing by Arun Koyyur)

    Carolina Brazil; ieconnects.ie.edu,